Myocardial ischemia/reperfusion (I/R) injury has become an important therapeutic target for ischemic heart disease, a leading cause of morbidity and mortality worldwide. Myocardial ischemia/reperfusion (I/R) injury has become an important therapeutic target for ischemic heart disease, a leading cause of morbidity and mortality worldwide. Currently, there is no effective treatment to reduce cardiac I/R injury.